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The modafinil is a neuro stimulant with neuroprotective properties indicated for the treatment of excessive daytime sleepiness associated with narcolepsy, excessive daytime sleepiness associated with obstructive sleep apnea and sleep disorder by changing work shift "shift work". Modafinil, like other stimulants, increases the release of monoamines, specifically norepinephrine and dopamine. However, Modafinil also increases the levels of histamine in the hypothalamus, which has contributed to its being considered a "waking state promoting agent" instead of a classic stimulant of the type of amphetamines. Despite its action on histamine, it partially shares the mode of action with other stimulants due to its effects on norepinephrine and dopamine. Modafinil is used in the treatment of benign prostatic hyperplasia (BPH) and high blood pressure.